"Imagine not being hungry all day without feeling side effects typical of diet pills, like a racing heart or queasy stomach."

CBS News, 60 Minutes, talking about Hoodia

Hoodia gordonii, "Whoo De AH", is the botanical name for a leafless, spiky succulent plant that grows throughout the semi-arid areas of Southern Africa primarily the Kalahari desert. The San (local inhabitants) have rationally used Hoodia stems to stave off hunger and thirst when on long journeys, as it acts as an appetite suppressant.

Hoodia is a Succulent botanical and is part of the Genus: Trichocaulon and belongs to the Family Name: Asclepiadaceae. There are approximately twenty plants within the Hoodia genus family, however, Hoodia Gordonii is the unique plant that South African San bushmen have used for generations to endure long hunting expeditions.

It basically tricks the brain into thinking that you're full. The chemical constituents in Hoodia work within the satiety center by releasing a chemical compound similar to glucose but much stronger. The hypothalamus in the brain receives this signal as an indication that enough food has been consumed and this in turn stunts the appetite.

Hoodia enhances your mood therefore you will not become irritable or weak while you are on the program. The San Tribe could go without food for 24 hours after eating Hoodia, and in the same process hunt for food in the harsh Kalahari desert. It is therefore also known to maintain a high energy level.

One of the active ingredients in the herb is a chemical compound called P57, which is thought to be at least partly responsible for the appetite-suppressing effects of hoodia gordonii. But this is probably an oversimplification, since herbs typically work with an assortment of chemical compounds, not just one chemical.

To understand how all this works, you have to understand what "hunger" really is in the first place. Hunger is just an illusion. It's a signal in your brain, a chemical message that causes you to feel certain feelings and, ultimately, act on them.

Normally, to get your hypothalamus to turn off the hunger switch, you'd have to eat a moderate amount of food. And your hypothalamus isn't very quick on the draw either: it takes around 20 minutes to figure out what you've eaten, and by that time, you've probably eaten another 800 calories. So by the time your hunger signal gets turned off, you've already overeaten yet again.

Eat this chemical, and your hypothalamus thinks you've just wolfed down three plates of food at the local buffet. Your hunger is abruptly cancelled. You just don't feel hungry anymore. Everything else is fine: there are no known side effects. But you simply don't feel like eating. At least that's what the hoodia companies explain you should experience.

The San Tribesmen, the original discovers of the plant, also say it makes you feel stronger, more energetic, and more focused. Nobody complains of any side effects whatsoever, and the plant has been chewed for literally thousand of years by various generations of the San, with no ill effects known whatsoever.

Hoodia pills are my life saver. I have a thyroid problem and this causes depression and weight gain. These pills take my hunger away so I can get back into shape and they make me happy, nice "side effect" ;-) Now my Doctor is taking them too! M S (Germany).

Thank you, the second Hoodia Gordonii shipment arrived yesterday April 4, 2005. By the way Hoodia is working very well I lost 12 lbs or (5.5 kg) in 2 months. Not dramatic but then again losing weight slowly is the best way to go. At this stage I don't pay attention to carbohydrates, fats, sugars and other diet fads. Regards - G D B (USA)

Hoodia was eaten as a fresh food by the San tribe for thousands of years with zero side effects.

As far as scientists know, there are no negative side-effects. The local san, whose ancestors have been using the plant for thousands of years, claim that there are no negative side effects. So Hoodia can be used in conjunction with prescription medications.

There are no known adverse side effects as a result of taking Hoodia in conjunction with prescription medications and other herbal supplements. However, if you are presently using any prescription medication and are under the care of a physician, you should always consult your physician before taking any supplement medication.

ow long Hoodia take to work? With-in one hour after taking 2 capsules, Hoodia will suppress your appetite for around 4-8 hours.

The pure Hoodia that contains appetite suppressant qualities is only grown in one specific region in South Africa. If the Hoodia is from China, USA or any other part of the world and is not accompanied by a South African Government Certificate of Authenticity, the product is inferior and ineffective.

Certainly any hoodia company out there that's selling an honest product is conducting a variety of testing, trying to find out who has counterfeit products and who has real products and trying to inform and educate their own customers about the fact that they have the real thing. But, as always, test results offered by companies who have financial interest in proving their product to be genuine simply don't carry the same weight as independent test results from an unbiased third company.

Hoodia is also known by horticulture experts as being extremely difficult to cultivate in captivity. The plants rot easily, and they won't grow in regular soil -- they need sandy soil with excellent drainage. Also, to make things even more difficult, these plants aren't pollinated by bees, they're pollinated by flies. To attract the flies, their blooms emit a strong, repulsive odor that smells a lot like rotting flesh.

After years of careful research, scientists isolated several compounds in this all-natural food that was responsible for dramatic weight loss, P57, which has been widely reported, is but one of several chemical compounds found in the Hoodia succulent. Not only was it proven completely safe, it contains no stimulates that could contribute to the jittery feeling associated with weight loss products of the last decade.

It has been established that the P57 molecule found in wild harvested Hoodia Gordonii works by mimicking the effect that glucose has on nerve cells in the brain in effect fooling the body into thinking it is full, even when it is not, thus curbing the appetite.

Mass global interest has been shown for Hoodia since Pfizer, the international pharmaceutical giant, started to research Hoodia's potential to help people with obesity. Pfizer recently discovered Hoodia and decided to invest millions into researching the plants benefits as a new drug that would help with obesity. The research published by this company has catapulted Hoodia into the international spotlight.

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